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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732874
Species: Mus musculus
RGD Object: Gene
Symbol: Nr0b2
Name: nuclear receptor subfamily 0, group B, member 2
Acc ID: CHEBI:16643
Term: L-methionine
Definition: The L-enantiomer of methionine.
Chemical ID: MESH:D008715
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr0b2multiple interactionsEXP 6480464CTD[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of NR0B2 mRNA; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of NR0B2 mRNA; NR0B2 protein promotes the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of CYP4A14 mRNA]; NR0B2 protein promotes the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with pirinixic acid] results in increased expression of CYP4A14 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]]; Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NR0B2 mRNA]PMID:19593819 PMID:25712622
Nr0b2multiple interactionsISONR0B2 (Homo sapiens)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NR0B2 mRNA]; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of NR0B2 mRNA; Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NR0B2 mRNA]PMID:25712622
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