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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71101
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc3
Name: ATP binding cassette subfamily C member 3
Acc ID: CHEBI:16643
Term: L-methionine
Definition: The L-enantiomer of methionine.
Chemical ID: MESH:D008715
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc3multiple interactionsEXP 6480464CTD[[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 protein] which results in increased export of Acetaminophen metabolite; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 mRNA; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 proteinPMID:17640958 PMID:24384915
Abcc3multiple interactionsISOAbcc3 (Mus musculus)6480464CTD[LEP gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 mRNA; [LEPR gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 mRNA; [LEPR gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 protein; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ABCC3 mRNAPMID:20938992 PMID:24384915
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