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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621496
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bhmt
Name: betaine-homocysteine S-methyltransferase
Acc ID: CHEBI:16643
Term: L-methionine
Definition: The L-enantiomer of methionine.
Chemical ID: MESH:D008715
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bhmtmultiple interactionsISOBHMT (Homo sapiens)6480464CTDMethionine inhibits the reaction [BHMT protein results in increased metabolism of Vitamin U]PMID:18230605
Bhmtmultiple interactionsISOBhmt (Mus musculus)6480464CTD[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of BHMT mRNAPMID:29127188
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