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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619570
Species: Homo sapiens
RGD Object: Gene
Symbol: MAPK3
Name: mitogen-activated protein kinase 3
Acc ID: CHEBI:16643
Term: L-methionine
Definition: The L-enantiomer of methionine.
Chemical ID: MESH:D008715
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAPK3multiple interactionsISOMapk3 (Rattus norvegicus)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Methionine deficiency co-treated with Cysteine deficiency] results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased phosphorylation of and results in increased activity of MAPK3 protein]PMID:11709198
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