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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2807
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxa1
Name: forkhead box A1
Acc ID: CHEBI:16643
Term: L-methionine
Definition: The L-enantiomer of methionine.
Chemical ID: MESH:D008715
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Foxa1multiple interactionsISOFoxa1 (Mus musculus)6480464CTD[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of FOXA1 gene; [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FOXA1 mRNA; Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FOXA1 mRNA]PMID:20938992 PMID:25712622
Foxa1multiple interactionsISOFOXA1 (Homo sapiens)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FOXA1 mRNA]; [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FOXA1 mRNA; Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FOXA1 mRNA]PMID:25712622
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