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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:16643
Term: L-methionine
Definition: The L-enantiomer of methionine.
Chemical ID: MESH:D008715
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1multiple interactionsISOCYP1A1 (Homo sapiens)6480464CTD[[Methionine co-treated with 6-formylindolo(3,2-b)carbazole] results in increased methylation of CYP1A1 promoter] which results in decreased expression of CYP1A1 mRNA; [Methionine co-treated with 6-formylindolo(3,2-b)carbazole] results in increased methylation of CYP1A1 promoterPMID:31626383
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