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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735591
Species: Homo sapiens
RGD Object: Gene
Symbol: IL10
Name: interleukin 10
Acc ID: CHEBI:16602
Term: trichloroethene
Definition: A member of the class of chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.
Chemical ID: MESH:D014241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL10decreases expressionISOIl10 (Rattus norvegicus)6480464CTDTrichloroethylene results in decreased expression of IL10 mRNAPMID:14565619
IL10increases expressionISOIl10 (Rattus norvegicus)6480464CTDTrichloroethylene results in increased expression of IL10 mRNAPMID:33387578
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