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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734109
Species: Mus musculus
RGD Object: Gene
Symbol: Gabbr1
Name: gamma-aminobutyric acid type B receptor subunit 1
Acc ID: CHEBI:16602
Term: trichloroethene
Definition: A member of the class of chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.
Chemical ID: MESH:D014241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabbr1decreases expressionISOGabbr1 (Rattus norvegicus)6480464CTDTrichloroethylene results in decreased expression of GABBR1 mRNAPMID:33387578
Gabbr1multiple interactionsISOGABBR1 (Homo sapiens)6480464CTDTrichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]PMID:10683198
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