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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733435
Species: Homo sapiens
RGD Object: Gene
Symbol: COL5A1
Name: collagen type V alpha 1 chain
Acc ID: CHEBI:16602
Term: trichloroethene
Definition: A member of the class of chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.
Chemical ID: MESH:D014241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
COL5A1decreases expressionISOCol5a1 (Rattus norvegicus)6480464CTDTrichloroethylene results in decreased expression of COL5A1 mRNAPMID:33387578
COL5A1increases methylationISOCol5a1 (Rattus norvegicus)6480464CTDTrichloroethylene results in increased methylation of COL5A1 genePMID:27618143
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