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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732685
Species: Mus musculus
RGD Object: Gene
Symbol: Acox1
Name: acyl-Coenzyme A oxidase 1, palmitoyl
Acc ID: CHEBI:16602
Term: trichloroethene
Definition: A member of the class of chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.
Chemical ID: MESH:D014241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acox1increases expressionEXP 6480464CTDTrichloroethylene results in increased expression of ACOX1 mRNA; Trichloroethylene results in increased expression of ACOX1 proteinPMID:20709644 PMID:23575800 PMID:26136231
Acox1multiple interactionsEXP 6480464CTDPPARA protein promotes the reaction [Trichloroethylene results in increased expression of and results in increased activity of ACOX1 protein]; Trichloroethylene results in increased expression of and results in increased activity of ACOX1 proteinPMID:15363585
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