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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620023
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chrm2
Name: cholinergic receptor, muscarinic 2
Acc ID: CHEBI:16595
Term: 1D-myo-inositol 1,4,5-trisphosphate
Definition: A myo-inositol trisphosphate that has formula C6H15O15P3.
Chemical ID: MESH:D015544
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrm2increases abundanceISOChrm2 (Mus musculus)6480464CTDCHRM2 protein results in increased abundance of Inositol 1,4,5-TrisphosphatePMID:19002953
Chrm2multiple interactionsISOChrm2 (Mus musculus)6480464CTDCarbachol promotes the reaction [CHRM2 protein results in increased abundance of Inositol 1,4,5-Trisphosphate]; otenzepad inhibits the reaction [Carbachol promotes the reaction [CHRM2 protein results in increased abundance of Inositol 1,4,5-Trisphosphate]]PMID:19002953
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