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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734431
Species: Homo sapiens
RGD Object: Gene
Symbol: NFE2L2
Name: nuclear factor, erythroid 2 like 2
Acc ID: CHEBI:16587
Term: 20-hydroxyecdysone
Definition: An ecdysteroid that is ecdysone substituted by a hydroxy group at position 20.
Chemical ID: MESH:D004441
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NFE2L2increases response to substanceISORGD:6203606480464CTDNFE2L2 results in increased susceptibility to EcdysteronePMID:26048653
NFE2L2multiple interactionsISORGD:6203606480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium affects the localization of NFE2L2 protein]]; Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium affects the localization of NFE2L2 protein]PMID:26048653
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