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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2750
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grpr
Name: gastrin releasing peptide receptor
Acc ID: CHEBI:16586
Term: 6-aminohexanoic acid
Definition: An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Chemical ID: MESH:D015119
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7319596480464CTD[2-(3-(1, 3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1, 3-carboxypropyl)-4, 7-carboxymethyl-1, 4, 7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [bombesin, Tyr(4)- binds to GRPR protein]

PMID:24508213
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.