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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2750
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grpr
Name: gastrin releasing peptide receptor
Acc ID: CHEBI:16586
Term: 6-aminohexanoic acid
Definition: An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Chemical ID: MESH:D015119
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grprmultiple interactionsISORGD:7319596480464CTD[2-3-1 3-dicarboxypropylureidopentanedioic acid binds to Aminocaproic Acid binds to 1-1 3-carboxypropyl-4 7-carboxymethyl-1 4 7-triazacyclononane binds to Valerates binds to bombesin 7-14 binds to Copper] inhibits the reaction [bombesin Tyr4- binds to GRPR protein]

PMID:24508213
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