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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309583
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tfeb
Name: transcription factor EB
Acc ID: CHEBI:16551
Term: alpha,alpha-trehalose
Definition: A trehalose in which both glucose residues have alpha-configuration at the anomeric carbon.
Chemical ID: MESH:D014199
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tfebaffects localizationISOTfeb (Mus musculus)6480464CTDTrehalose affects the localization of TFEB proteinPMID:30335591
Tfebmultiple interactionsISOTfeb (Mus musculus)6480464CTDCyclosporine inhibits the reaction [Trehalose affects the localization of TFEB protein]; PPP3CB affects the reaction [Trehalose affects the localization of TFEB protein]; TFEB affects the reaction [Trehalose results in increased expression of CTSB mRNA]; TFEB affects the reaction [Trehalose results in increased expression of LAMP2 mRNA]; TFEB affects the reaction [Trehalose results in increased expression of MAP1LC3B mRNA]; TFEB affects the reaction [Trehalose results in increased expression of MCOLN1 mRNA]; TFEB affects the reaction [Trehalose results in increased expression of PPARGC1A mRNA]; TFEB affects the reaction [Trehalose results in increased expression of SQSTM1 mRNA]; TFEB affects the reaction [Trehalose results in increased expression of TPP1 mRNA]PMID:30335591
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