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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737482
Species: Homo sapiens
RGD Object: Gene
Symbol: BIRC5
Name: baculoviral IAP repeat containing 5
Acc ID: CHEBI:165219
Term: PCB138
Definition: null
Chemical ID: MESH:C029790
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BIRC5multiple interactionsISOBirc5 (Mus musculus)6480464CTD2,2',3',4,4',5-hexachlorobiphenyl inhibits the reaction [[Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of BIRC5 protein]; 2,2',3',4,4',5-hexachlorobiphenyl inhibits the reaction [TNF protein results in decreased expression of BIRC5 protein]; [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BIRC5 mRNAPMID:25510870 PMID:29704545
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