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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:16509
Term: 1,4-benzoquinone
Definition: The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
Chemical ID: MESH:C004532
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NQO1increases expressionEXP 6480464CTDquinone results in increased expression of NQO1 mRNA; quinone results in increased expression of NQO1 proteinPMID:20491607 PMID:21059386 PMID:28645578 PMID:8652659
NQO1increases expressionISONqo1 (Mus musculus)6480464CTDquinone results in increased expression of NQO1 proteinPMID:25437431
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