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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735516
Species: Homo sapiens
RGD Object: Gene
Symbol: BCL2L1
Name: BCL2 like 1
Acc ID: CHEBI:16480
Term: nitric oxide
Definition: A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom.
Chemical ID: MESH:D009569
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BCL2L1decreases expressionEXP 6480464CTDNitric Oxide results in decreased expression of BCL2L1 proteinPMID:15126337
BCL2L1increases expressionISOBcl2l1 (Rattus norvegicus)6480464CTDNitric Oxide results in increased expression of BCL2L1 mRNAPMID:25726415
BCL2L1multiple interactionsISOBcl2l1 (Rattus norvegicus)6480464CTDGATA5 protein promotes the reaction [Nitric Oxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2L1 mRNA]]; GATA5 protein promotes the reaction [Nitric Oxide results in increased expression of BCL2L1 mRNA]; Nitric Oxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2L1 mRNA]; Nitric Oxide results in increased expression of and affects the localization of BCL2L1 proteinPMID:25726415
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