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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col1a2
Name: collagen type I alpha 2 chain
Acc ID: CHEBI:16480
Term: nitric oxide
Definition: A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom.
Chemical ID: MESH:D009569
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDNitric Oxide deficiency results in increased expression of COL1A2 mRNA

PMID:10445667
multiple interactionsEXP 6480464CTDAmlodipine inhibits the reaction [Nitric Oxide deficiency results in increased expression of COL1A2 mRNA]

PMID:10445667
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.