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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:16480
Term: nitric oxide
Definition: A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom.
Chemical ID: MESH:D009569
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:107966480464CTDIL4 protein inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide]

PMID:12612912
multiple interactionsISORGD:7363066480464CTDIL4 protein inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]

PMID:12115740
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.