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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1603713
Species: Homo sapiens
RGD Object: Gene
Symbol: KNG1
Name: kininogen 1
Acc ID: CHEBI:16480
Term: nitric oxide
Definition: A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom.
Chemical ID: MESH:D009569
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KNG1increases abundanceEXP 6480464CTDKNG1 protein results in increased abundance of Nitric OxidePMID:10535458
KNG1affects abundanceISOKng1 (Mus musculus)6480464CTDKNG1 affects the abundance of Nitric OxidePMID:16514058
KNG1increases secretionISOKng1 (Rattus norvegicus)6480464CTDKNG1 protein results in increased secretion of Nitric OxidePMID:16733097
KNG1multiple interactionsISOKng1 (Mus musculus)6480464CTDPD 123319 affects the reaction [KNG1 affects the abundance of Nitric Oxide]PMID:16514058
KNG1multiple interactionsISOKng1 (Rattus norvegicus)6480464CTD[KNG1 protein modified form binds to and results in increased activity of BDKRB2 protein] which results in increased chemical synthesis of Nitric Oxide; Lipopolysaccharides promotes the reaction [KNG1 protein modified form results in increased chemical synthesis of Nitric Oxide]PMID:29775649
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