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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11003
Species: Mus musculus
RGD Object: Gene
Symbol: Nppa
Name: natriuretic peptide type A
Acc ID: CHEBI:16480
Term: nitric oxide
Definition: A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom.
Chemical ID: MESH:D009569
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nppaincreases expressionISONppa (Rattus norvegicus)6480464CTDNitric Oxide deficiency results in increased expression of NPPA mRNA; Nitric Oxide deficiency results in increased expression of NPPA proteinPMID:10397678 PMID:12198334 PMID:14700747 PMID:15177930
Nppamultiple interactionsISONppa (Rattus norvegicus)6480464CTDLosartan inhibits the reaction [Nitric Oxide deficiency results in increased expression of NPPA mRNA]PMID:12198334
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