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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3651
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cxcl12
Name: C-X-C motif chemokine ligand 12
Acc ID: CHEBI:16470
Term: glyceollin
Definition: An organic heteropentacyclic compound that has formula C20H18O5.
Chemical ID: MESH:C017343
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl12multiple interactionsISORGD:7372236480464CTD[Tamoxifen co-treated with glyceollin] results in decreased expression of CXCL12 mRNA; glyceollin inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]; glyceollin inhibits the reaction [Estrogens results in increased expression of CXCL12 mRNA]PMID:19797619
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