GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SNAI2 | affects expression | EXP | | 6480464 | CTD | Estradiol affects the expression of SNAI2 mRNA | PMID:22574217 | SNAI2 | decreases expression | EXP | | 6480464 | CTD | Estradiol results in decreased expression of SNAI2 protein | PMID:15955695 | SNAI2 | increases expression | EXP | | 6480464 | CTD | Estradiol results in increased expression of SNAI2 mRNA; Estradiol results in increased expression of SNAI2 protein | PMID:25690688 PMID:28844962 PMID:32234386 PMID:32387340 PMID:35044086 | SNAI2 | multiple interactions | EXP | | 6480464 | CTD | 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of SNAI2 protein]; [Arsenic co-treated with Estradiol] results in decreased expression of SNAI2 mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of SNAI2 mRNA; AG 1879 inhibits the reaction [Estradiol results in increased expression of SNAI2 protein]; ESR1 protein alternative form promotes the reaction [Estradiol results in increased expression of SNAI2 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of SNAI2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of SNAI2 protein]; plerixafor inhibits the reaction [Estradiol results in increased expression of SNAI2 protein] | PMID:25690688 PMID:28844962 PMID:30165855 PMID:33047385 PMID:35044086 | | ||||||||||||||||||||||
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