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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735427
Species: Mus musculus
RGD Object: Gene
Symbol: Cish
Name: cytokine inducible SH2-containing protein
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cishdecreases expressionEXP 6480464CTDEstradiol results in decreased expression of CISH mRNAPMID:19484750
Cishmultiple interactionsEXP 6480464CTDEstradiol inhibits the reaction [IL1B protein results in increased expression of CISH mRNA]PMID:12072388
Cishaffects expressionISOCish (Rattus norvegicus)6480464CTDEstradiol affects the expression of CISH mRNAPMID:32145629
Cishincreases expressionISOCish (Rattus norvegicus)6480464CTDEstradiol results in increased expression of CISH mRNAPMID:18162529
Cishincreases expressionISOCISH (Homo sapiens)6480464CTDEstradiol results in increased expression of CISH mRNAPMID:23019147 PMID:31614463 PMID:36828454
Cishmultiple interactionsISOCish (Rattus norvegicus)6480464CTDEstradiol promotes the reaction [Sulpiride results in increased expression of CISH mRNA]PMID:18162529
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