Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735300
Species: Mus musculus
RGD Object: Gene
Symbol: Cxcr2
Name: C-X-C motif chemokine receptor 2
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcr2affects expressionISOCXCR2 (Homo sapiens)6480464CTDEstradiol affects the expression of CXCR2 mRNA; Estradiol affects the expression of CXCR2 proteinPMID:19401270
Cxcr2multiple interactionsISOCxcr2 (Rattus norvegicus)6480464CTD[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CXCR2 mRNA; Estradiol inhibits the reaction [Cholesterol, Dietary results in increased expression of CXCR2 mRNA]; Estradiol inhibits the reaction [Cholesterol, Dietary results in increased expression of CXCR2 protein]PMID:12852833 PMID:32741896
Cxcr2multiple interactionsISOCXCR2 (Homo sapiens)6480464CTD[Estradiol co-treated with TGFB1 protein] results in decreased expression of CXCR2 mRNAPMID:30165855
Go Back to source page   Continue to Ontology report