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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733604
Species: Mus musculus
RGD Object: Gene
Symbol: Apoe
Name: apolipoprotein E
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoedecreases expressionEXP 6480464CTDEstradiol results in decreased expression of APOE mRNAPMID:25210133
Apoeincreases expressionEXP 6480464CTDEstradiol results in increased expression of APOE mRNAPMID:19484750
Apoemultiple interactionsEXP 6480464CTDESR1 protein promotes the reaction [Estradiol results in decreased expression of APOE mRNA]PMID:25210133
Apoedecreases expressionISOAPOE (Homo sapiens)6480464CTDEstradiol results in decreased expression of APOE mRNAPMID:31614463
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