Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732433
Species: Mus musculus
RGD Object: Gene
Symbol: Itgam
Name: integrin alpha M
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itgamincreases expressionEXP 6480464CTDEstradiol results in increased expression of ITGAM mRNA; Estradiol results in increased expression of ITGAM proteinPMID:19484750 PMID:28811679
Itgammultiple interactionsISOITGAM (Homo sapiens)6480464CTD[Estradiol co-treated with Norethindrone Acetate] results in increased expression of ITGAM mRNAPMID:22217510
Itgammultiple interactionsISOItgam (Rattus norvegicus)6480464CTD[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ITGAM mRNA; Estradiol inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of ITGAM protein]PMID:29425760 PMID:32741896
Go Back to source page   Continue to Ontology report