GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Itgam | increases expression | EXP | | 6480464 | CTD | Estradiol results in increased expression of ITGAM mRNA; Estradiol results in increased expression of ITGAM protein | PMID:19484750 PMID:28811679 | Itgam | multiple interactions | ISO | ITGAM (Homo sapiens) | 6480464 | CTD | [Estradiol co-treated with Norethindrone Acetate] results in increased expression of ITGAM mRNA | PMID:22217510 | Itgam | multiple interactions | ISO | Itgam (Rattus norvegicus) | 6480464 | CTD | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ITGAM mRNA; Estradiol inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of ITGAM protein] | PMID:29425760 PMID:32741896 | |
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