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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fgf8
Name: fibroblast growth factor 8
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf8multiple interactionsISOFgf8 (Mus musculus)6480464CTDFGF8 protein inhibits the reaction [FSHB protein results in increased abundance of Estradiol]PMID:22366471
Fgf8multiple interactionsISOFGF8 (Homo sapiens)6480464CTD[BMP15 protein co-treated with GDF9 protein] promotes the reaction [FGF8 protein inhibits the reaction [FSHB protein results in increased abundance of Estradiol]]; GDF9 protein promotes the reaction [FGF8 protein inhibits the reaction [FSHB protein results in increased abundance of Estradiol]]PMID:22366471
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