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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69356
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lgals3
Name: galectin 3
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:7363056480464CTDEstradiol affects the expression of LGALS3 mRNA

PMID:15598610
increases expressionISORGD:7363056480464CTDEstradiol results in increased expression of LGALS3 mRNA

PMID:15289156
multiple interactionsISORGD:7363046480464CTD[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of LGALS3 mRNA, [Estradiol co-treated with Progesterone] results in decreased expression of LGALS3 mRNA

PMID:20660070, PMID:20823114
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.