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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68563
Species: Mus musculus
RGD Object: Gene
Symbol: Slc7a2
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc7a2affects expressionISOSlc7a2 (Rattus norvegicus)6480464CTDEstradiol affects the expression of SLC7A2 mRNAPMID:32145629
Slc7a2decreases expressionISOSLC7A2 (Homo sapiens)6480464CTDEstradiol results in decreased expression of SLC7A2 mRNAPMID:21185374
Slc7a2increases expressionISOSLC7A2 (Homo sapiens)6480464CTDEstradiol results in increased expression of SLC7A2 mRNAPMID:19167446 PMID:32387340 PMID:36828454
Slc7a2multiple interactionsISOSLC7A2 (Homo sapiens)6480464CTD[Progesterone co-treated with Estradiol] results in increased expression of SLC7A2 mRNAPMID:17404688
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