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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621061
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kat5
Name: lysine acetyltransferase 5
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kat5multiple interactionsISOKAT5 (Homo sapiens)6480464CTDEstradiol inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]; Estradiol promotes the reaction [ESR1 protein binds to KAT5 protein]PMID:23857583 PMID:29389661 PMID:32088792
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