GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bmp7 | decreases expression | EXP | | 6480464 | CTD | Estradiol results in decreased expression of BMP7 mRNA | PMID:15680359 | Bmp7 | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with Estradiol] results in decreased expression of BMP7 mRNA; [BMP7 protein results in increased expression of CYP19A1 mRNA] promotes the reaction [FSHB protein results in increased abundance of Estradiol]; [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of BMP7 mRNA; [Testosterone co-treated with Estradiol] results in decreased expression of BMP7 mRNA; BMP7 protein inhibits the reaction [IGF1 protein promotes the reaction [FSHB protein results in increased abundance of Estradiol]] | PMID:22067323 PMID:26496021 PMID:32741896 | Bmp7 | decreases expression | ISO | BMP7 (Homo sapiens) | 6480464 | CTD | Estradiol results in decreased expression of BMP7 mRNA | PMID:14994273 PMID:19167446 PMID:24758408 | Bmp7 | decreases expression | ISO | Bmp7 (Mus musculus) | 6480464 | CTD | Estradiol results in decreased expression of BMP7 mRNA | PMID:14994273 | Bmp7 | increases expression | ISO | BMP7 (Homo sapiens) | 6480464 | CTD | Estradiol results in increased expression of BMP7 mRNA | PMID:19619570 PMID:31646340 | Bmp7 | increases expression | ISO | Bmp7 (Mus musculus) | 6480464 | CTD | Estradiol results in increased expression of BMP7 mRNA | PMID:19484750 | Bmp7 | multiple interactions | ISO | BMP7 (Homo sapiens) | 6480464 | CTD | [Estradiol co-treated with Progesterone] results in decreased expression of BMP7 mRNA; [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of BMP7 mRNA; BMP7 protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of IGFBP1 mRNA]; BMP7 protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of IGFBP1 protein]; EGF protein inhibits the reaction [Estradiol results in decreased expression of BMP7 mRNA] | PMID:19619570 PMID:20085912 PMID:24758408 | | ||||||||||||||||||||||
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