GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fgfr3 | increases expression | ISO | FGFR3 (Homo sapiens) | 6480464 | CTD | Estradiol results in increased expression of FGFR3 mRNA alternative form | PMID:14602803 | Fgfr3 | increases expression | ISO | Fgfr3 (Mus musculus) | 6480464 | CTD | Estradiol results in increased expression of FGFR3 mRNA | PMID:25210133 | Fgfr3 | multiple interactions | ISO | FGFR3 (Homo sapiens) | 6480464 | CTD | [Estradiol binds to ESR2 protein] which results in increased expression of FGFR3 mRNA; [Estradiol co-treated with TGFB1 protein] results in decreased expression of FGFR3 mRNA | PMID:20404318 PMID:30165855 | Fgfr3 | multiple interactions | ISO | Fgfr3 (Mus musculus) | 6480464 | CTD | ESR1 protein promotes the reaction [Estradiol results in increased expression of FGFR3 mRNA] | PMID:25210133 | |
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