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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61967
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mcm6
Name: minichromosome maintenance complex component 6
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mcm6affects expressionEXP 6480464CTDEstradiol affects the expression of MCM6 mRNAPMID:32145629
Mcm6increases expressionISOMCM6 (Homo sapiens)6480464CTDEstradiol results in increased expression of MCM6 mRNAPMID:16474171 PMID:17622325 PMID:19167446
Mcm6multiple interactionsISOMCM6 (Homo sapiens)6480464CTD[Estradiol co-treated with Parathion] results in increased expression of MCM6 mRNAPMID:17622325
Mcm6multiple interactionsISOMcm6 (Mus musculus)6480464CTDEstradiol inhibits the reaction [Progesterone affects the localization of MCM6 protein]PMID:16966611
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