GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3911
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tshr
Name: thyroid stimulating hormone receptor
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7370216480464CTDEstradiol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP]

PMID:19766106
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.