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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3649
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sdc2
Name: syndecan 2
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sdc2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of SDC2 mRNAPMID:26496021
Sdc2increases expressionISOSDC2 (Homo sapiens)6480464CTDEstradiol results in increased expression of SDC2 mRNAPMID:17121429 PMID:19167446 PMID:19619570 PMID:21185374
Sdc2multiple interactionsISOSDC2 (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SDC2 mRNA; [Estradiol co-treated with TGFB1 protein] results in decreased expression of SDC2 mRNAPMID:19619570 PMID:30165855
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