GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl3 | multiple interactions | EXP | | 6480464 | CTD | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CCL3 mRNA; [Estradiol co-treated with Progesterone] results in increased expression of CCL3 mRNA; Estradiol inhibits the reaction [Estrogens deficiency results in increased expression of CCL3 protein] | PMID:19553526 PMID:21277368 PMID:32741896 | Ccl3 | increases expression | ISO | Ccl3 (Mus musculus) | 6480464 | CTD | Estradiol results in increased expression of CCL3 mRNA | PMID:19484750 | Ccl3 | multiple interactions | ISO | CCL3 (Homo sapiens) | 6480464 | CTD | [Estradiol binds to ESR2 protein] which results in decreased expression of CCL3 mRNA | PMID:20404318 | |
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