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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3568
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rgs5
Name: regulator of G-protein signaling 5
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rgs5increases expressionEXP 6480464CTDEstradiol results in increased expression of RGS5 mRNAPMID:32145629
Rgs5decreases expressionISORGS5 (Homo sapiens)6480464CTDEstradiol results in decreased expression of RGS5 mRNAPMID:21795739
Rgs5decreases expressionISORgs5 (Mus musculus)6480464CTDEstradiol results in decreased expression of RGS5 mRNAPMID:19484750
Rgs5multiple interactionsISORGS5 (Homo sapiens)6480464CTD[Progesterone co-treated with Estradiol] results in decreased expression of RGS5 mRNAPMID:17404688
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