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RGD ID: 3438
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgis
Name: prostaglandin I2 synthase
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgisdecreases expression EXP 401960094RGDBeta-estradiol decreases expression of Ptgis protein in aortic endothelial cells 
Ptgisincreases expression EXP 401960078RGD17beta-estradiol increases expression of Ptgis protein in cerebral blood vessels 
Ptgisincreases expressionISOPtgis (Mus musculus)6480464CTDEstradiol results in increased expression of PTGIS mRNAPMID:19484750
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