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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3236
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Otc
Name: ornithine transcarbamylase
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Otcmultiple interactionsEXP 6480464CTDEstradiol promotes the reaction [PRL protein results in increased activity of OTC protein]PMID:3097147
Otcdecreases expressionISOOTC (Homo sapiens)6480464CTDEstradiol results in decreased expression of OTC mRNAPMID:20106945
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