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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3227
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Odc1
Name: ornithine decarboxylase 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Odc1decreases expressionEXP 6480464CTDEstradiol results in decreased expression of ODC1 mRNAPMID:32145629
Odc1increases expressionEXP 6480464CTDEstradiol results in increased expression of ODC1 mRNAPMID:17522070
Odc1affects expressionISOODC1 (Homo sapiens)6480464CTDEstradiol affects the expression of ODC1 mRNAPMID:22574217
Odc1decreases expressionISOODC1 (Homo sapiens)6480464CTDEstradiol results in decreased expression of ODC1 mRNAPMID:21185374
Odc1increases expressionISOODC1 (Homo sapiens)6480464CTDEstradiol results in increased expression of ODC1 mRNAPMID:31614463
Odc1multiple interactionsISOODC1 (Homo sapiens)6480464CTDRotenone inhibits the reaction [Estradiol results in increased activity of ODC1 protein]PMID:9834970
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