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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2679
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gfap
Name: glial fibrillary acidic protein
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gfapincreases expressionEXP 6480464CTDEstradiol results in increased expression of GFAP mRNAPMID:32145629
Gfapmultiple interactionsEXP 6480464CTDEstradiol affects the reaction [Estrogens deficiency results in increased expression of GFAP protein alternative form]PMID:30565903
Gfapmultiple interactionsISOGfap (Mus musculus)6480464CTD[Estradiol co-treated with Progesterone] promotes the reaction [Cuprizone results in increased expression of GFAP mRNA]PMID:19031445
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