GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Adm | decreases expression | EXP | | 6480464 | CTD | Estradiol results in decreased expression of ADM mRNA | PMID:32145629 | Adm | increases abundance | EXP | | 6480464 | CTD | ADM protein results in increased abundance of Estradiol | PMID:21824440 | Adm | multiple interactions | EXP | | 6480464 | CTD | [Testosterone co-treated with Estradiol] results in increased expression of ADM mRNA; ADM protein inhibits the reaction [FSHB protein results in increased secretion of Estradiol] | PMID:18401014 PMID:32741896 | Adm | affects expression | ISO | ADM (Homo sapiens) | 6480464 | CTD | Estradiol affects the expression of ADM mRNA | PMID:22574217 | Adm | affects expression | ISO | Adm (Mus musculus) | 6480464 | CTD | Estradiol affects the expression of ADM mRNA | PMID:15598610 | Adm | decreases expression | ISO | ADM (Homo sapiens) | 6480464 | CTD | Estradiol results in decreased expression of ADM mRNA | PMID:17121429 | Adm | multiple interactions | ISO | ADM (Homo sapiens) | 6480464 | CTD | [Estradiol binds to ESR2 protein] which results in decreased expression of ADM mRNA; [Estradiol co-treated with Norethindrone Acetate] results in increased expression of ADM mRNA; CALCA protein modified form inhibits the reaction [ADM protein inhibits the reaction [FSHB protein results in increased secretion of Estradiol]] | PMID:18401014 PMID:20404318 PMID:22217510 | | ||||||||||||||||||||||
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