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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1620364
Species: Mus musculus
RGD Object: Gene
Symbol: Fbxl7
Name: F-box and leucine-rich repeat protein 7
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fbxl7increases expressionISOFBXL7 (Homo sapiens)6480464CTDEstradiol results in increased expression of FBXL7 mRNAPMID:31614463
Fbxl7multiple interactionsISOFBXL7 (Homo sapiens)6480464CTD[Estradiol co-treated with Progesterone] results in decreased expression of FBXL7 mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of FBXL7 mRNAPMID:20660070 PMID:30165855
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