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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1614946
Species: Mus musculus
RGD Object: Gene
Symbol: Trio
Name: triple functional domain (PTPRF interacting)
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trioaffects expressionISOTRIO (Homo sapiens)6480464CTDEstradiol affects the expression of TRIO mRNAPMID:22574217
Triodecreases expressionISOTRIO (Homo sapiens)6480464CTDEstradiol results in decreased expression of TRIO mRNAPMID:21795739
Trioincreases expressionISOTrio (Rattus norvegicus)6480464CTDEstradiol results in increased expression of TRIO mRNAPMID:32145629
Trioincreases expressionISOTRIO (Homo sapiens)6480464CTDEstradiol results in increased expression of TRIO mRNAPMID:31614463
Triomultiple interactionsISOTRIO (Homo sapiens)6480464CTD[Estradiol co-treated with TGFB1 protein] results in increased expression of TRIO mRNA; [Parathion co-treated with Estradiol] results in increased expression of TRIO proteinPMID:17622325 PMID:30165855
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