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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563152
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srgap3
Name: SLIT-ROBO Rho GTPase activating protein 3
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDEstradiol results in decreased expression of SRGAP3 mRNA

PMID:26945725
affects expressionISORGD:13453096480464CTDEstradiol affects the expression of SRGAP3 mRNA

PMID:25321415
multiple interactionsISORGD:13453096480464CTD[Estradiol co-treated with TGFB1 protein] results in decreased expression of SRGAP3 mRNA

PMID:30165855
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.