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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552819
Species: Mus musculus
RGD Object: Gene
Symbol: Aurka
Name: aurora kinase A
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aurkaincreases expressionEXP 6480464CTDEstradiol results in increased expression of AURKA mRNAPMID:25210133
Aurkamultiple interactionsEXP 6480464CTDESR1 protein promotes the reaction [Estradiol results in increased expression of AURKA mRNA]PMID:25210133
Aurkaaffects expressionISOAurka (Rattus norvegicus)6480464CTDEstradiol affects the expression of AURKA mRNAPMID:32145629
Aurkaincreases expressionISOAURKA (Homo sapiens)6480464CTDEstradiol results in increased expression of AURKA mRNAPMID:16474171 PMID:16514628 PMID:17268063 PMID:19167446 PMID:20106945
Aurkamultiple interactionsISOAURKA (Homo sapiens)6480464CTD[Arsenic co-treated with Estradiol] results in increased expression of AURKA mRNAPMID:33047385
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