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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551616
Species: Mus musculus
RGD Object: Gene
Symbol: Hdac5
Name: histone deacetylase 5
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hdac5affects expressionEXP 6480464CTDEstradiol affects the expression of HDAC5 mRNAPMID:15598610
Hdac5decreases expressionISOHDAC5 (Homo sapiens)6480464CTDEstradiol results in decreased expression of HDAC5 mRNAPMID:24758408 PMID:31614463 PMID:32030086
Hdac5multiple interactionsISOHDAC5 (Homo sapiens)6480464CTDEGF protein inhibits the reaction [Estradiol results in decreased expression of HDAC5 mRNA]PMID:24758408
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