GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CXCL10 | increases expression | EXP | | 6480464 | CTD | Estradiol results in increased expression of CXCL10 mRNA; Estradiol results in increased expression of CXCL10 protein | PMID:15557169 PMID:31614463 | CXCL10 | multiple interactions | EXP | | 6480464 | CTD | [Estradiol co-treated with TGFB1 protein] results in decreased expression of CXCL10 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of CXCL10 mRNA; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL10 mRNA] | PMID:15557169 PMID:17404688 PMID:30165855 | CXCL10 | increases expression | ISO | Cxcl10 (Rattus norvegicus) | 6480464 | CTD | Estradiol results in increased expression of CXCL10 mRNA | PMID:35192832 | CXCL10 | multiple interactions | ISO | Cxcl10 (Mus musculus) | 6480464 | CTD | Estradiol inhibits the reaction [Dimethoate results in increased expression of CXCL10 mRNA]; Estradiol inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA]; Estradiol inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 protein]; fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dimethoate results in increased expression of CXCL10 mRNA]] | PMID:19533603 PMID:23943137 | |
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