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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343162
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP4
Name: caspase 4
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP4affects expressionEXP 6480464CTDEstradiol affects the expression of CASP4 mRNAPMID:22574217
CASP4increases expressionEXP 6480464CTDEstradiol results in increased expression of CASP4 mRNAPMID:23373633 PMID:24481588
CASP4multiple interactionsEXP 6480464CTD[Estradiol co-treated with TGFB1 protein] results in decreased expression of CASP4 mRNAPMID:30165855
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